Resveratrol as an enhancer of apoptosis in cancer: a mechanistic review

M Ashrafizadeh, S Taeb… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
… , that p53 has a key role in the anti-cancer activity of resveratrol [54]. … Induction of sirtuin-1
signaling by resveratrol induces human chondrosarcoma cell apoptosis and exhibits antitumor

An update on current and future treatment options for chondrosarcoma

IJ MacDonald, CY Lin, SJ Kuo, CM Su… - … Review of Anticancer …, 2019 - Taylor & Francis
… of PI3K/Akt and p38 MAPK signaling pathways [Citation55], while … induction of apoptosis
and antitumor activity of resveratrol involves the activation of sirtuin 1 (Sirt1) in human CS cells […

Resveratrol in management of bone and spinal cancers

G Chen, H Xia, Z Zhang, H Yu - Natural product research, 2019 - Taylor & Francis
Resveratrol is able to induce apoptotic cell death and a … 3 (STAT3) signalling pathway by
activating sirtuin 1 (Sirt1) (Jin … The dosage for resveratrol to display anticancer effect in vitro is …

Resveratrol's anti-cancer effects through the modulation of tumor glucose metabolism

A Brockmueller, S Sameri, A Liskova, K Zhai… - Cancers, 2021 - mdpi.com
… fruits and vegetables exhibit promising therapeutic potential … Finally, resveratrol-induced
ER-stress leads to apoptosis of … Resveratrol upregulates sirtuin 1 (Sirt1); Sirt1-dependent …

Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: A Review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
… apples, has been reported to exhibit a wide range of biological … of resveratrol and increase
its anticancer activity are … to induce the formation of the death-inducing signaling complex (…

[PDF][PDF] Protective effect of resveratrol on knee osteoarthritis and its molecular mechanisms: a recent review in preclinical and clinical trials

S Yang, M Sun, X Zhang - Frontiers in Pharmacology, 2022 - frontiersin.org
… that RES can exhibit a biphasic dose-effect. In ethanol-induced cell death models, RES is …
pathway, RES can also modulate multiple other signaling pathways that mediate apoptosis

A pharmacological review on SIRT 1 and SIRT 2 proteins, activators, and inhibitors: Call for further research

M Nandave, R Acharjee, K Bhaduri, J Upadhyay… - International Journal of …, 2023 - Elsevier
… suggests that resveratrol-generated apoptosis is caused by … It induced the cell cycle arrest
of glioma cells and apoptosis … the anticancer effect of JGB1741 on three different tumor cell

Differential methylation and acetylation as the epigenetic basis of resveratrol's anticancer activity

M Farhan, MF Ullah, M Faisal, AA Farooqi… - Medicines, 2019 - mdpi.com
… activation of sirtuin 1, a deacetylase, by resveratrol has been … It is now believed that resveratrol
exhibits both antioxidant and … expression, this action of resveratrol induced the expression …

Effect of SIRT1 activators and inhibitors on CD44+/CD133+‑enriched non‑small cell lung cancer cells

Z Eroglu, C Erdem, G Oktem… - Molecular …, 2020 - spandidos-publications.com
… the mRNA and protein expression of sirtuin 1 (SIRT1) and p53 … to have an antitumor effect
by inducing cell apoptosis via the … that resveratrol is an important agent for inducing apoptosis

Beneficial Oxidative Stress-Related trans-Resveratrol Effects in the Treatment and Prevention of Breast Cancer

A Quarta, A Gaballo, B Pradhan, S Patra, M Jena… - Applied Sciences, 2021 - mdpi.com
… protein kinase (AMPK)/sirtuin 1 (SIRT1)/peroxisome proliferator-… Resveratrol can induce
cancer cell death through the … mechanism underlying the anticancer effect of resveratrol in both …